Should IC Patients Eat Nightshade Foods?

What Are Nightshades? 

Nightshades are a diverse group of foods, herbs, shrubs, and trees that have fascinated scientists, doctors, and nutritionists for centuries. To give you an idea of the diversity associated with this group of plants, consider the fact that tobacco, morning glory, potato, and tomato are all classified as nightshades. 

The ones that concern us in the Western diet mainly include tomatoes, potatoes (not sweet potatoes or yams), eggplant and peppers—this means all peppers including chili peppers, habenero, cayenne pepper and paprika (not peppercorns). Paprika is a sneaky one, showing up in lots of flavoring mixes and often under “spices” on ingredient labels. Other nightshades include goji berries (the new darling of the antioxidant crowd), ashwagandha (an adaptogenic herb from Ayurvedic medicine), Cape gooseberries (not normal gooseberries), ground cherries and garden huckleberries (not blueberries).

A particular group of substances in these foods, called alkaloids, can impact nerve-muscle function and digestive function in animals and humans, and may also be able to compromise joint function. Because the amount of alkaloids is very low in nightshade foods when compared with other nightshade plants, health problems from nightshade foods may only occur in individuals who are especially sensitive to these alkaloid substances. Since cooking only lowers alkaloid content of nightshade foods by about 40-50%, highly sensitive individuals may want to avoid this category of food altogether, while non-sensitive individuals may be able to eat these foods, especially in cooked form, without problem. Green and sprouted spots on potatoes usually reflect high alkaloid content, even though the green itself involves the presence of chlorophyll, not alkaloids. For this reason, sprouted areas should always be thoroughly removed before potato cooking, or the potatoes should be discarded altogether.

Potatoes naturally produce solanine and chaconine, a related glycoalkaloid, as a defense mechanism against insects, disease and predators (humans included). Potato leaves, stems and shoots are naturally high in these glycoalkaloids. When potato tubers are exposed to light, they turn green and increase glycoalkaloid production. This is a natural defense to help prevent the uncovered tuber from being eaten.

In potato tubers, 30–80 percent of the solanine develops in and close to the skin. If the potato looks green under the skin, throw it away; likewise if it has begun to sprout, just discard it.

Solanine and related glycoalkaloids are poisonous because they are acetylcholinesterase inhibitors—they inhibit the breakdown of acetylcholine, resulting in increased level and duration of action of this neurotransmitter. What does this mean? They cause prolonged muscle contractions. This is why people who are sensitive to nightshades or eat a lot of them often feel stiff when they wake up in the morning or sit for extended periods.

If you are going to eat potatoes, choose sweet potatoes and or red bliss, fingerling, the smaller potatoes have more fiber and less alkaloids.  It may also be wise to give them up and maybe introduce them a little at a time back into your diet and be sure to peel them.

I’m a whole health educator, I have been studying food for a long time now, and I will admit right off the bat that I am biased against nightshades. I used to eat a ton of foods in the nightshade family, but now I avoid them as much as possible. I am one of those who is very sensitive to these foods. I spend more than a dozen hours per week talking with woman and men who have chronic bladder and or pelvic pain and my goal is to help them get pain relief. In my opinion, and my personal experience,  pain management—that is, long-term painkillers, without a goal of true pain relief—will never resolve your pain.  For me and many of others, nightshade avoidance is the answer to long-term relief from pain.

Why should you care about this? It’s likely that you enjoy eating these foods and can’t imagine that they are bad for you in any way. Well, if you suffer from inflammation, joint, muscle and nerve pain, avoiding nightshades will lessen your pain, whether or not the nightshades are the true source of the pain. Are you sensitive to weather changes? This can be an indication of nightshade sensitivity. Muscle pain and tightness, morning stiffness, poor healing, arthritis, insomnia and gall bladder problems—these can all be caused by nightshades. Nightshades can also cause heart burn or GERD—a lot of people already know they react this way when they eat peppers or tomatoes.

Like soy, most nightshades are relative newcomers to European/Western diets. The tomato came to North America in the very early eighteenth century. It was termed the “love apple” and grown first as an ornamental. That means people grew it because it is pretty, yet they did not eat it. Why did they not eat it? They thought the tomato was poisonous. The leaves of the nightshade family are indeed overtly poisonous (livestock farmers know this well) and people avoided the tomato as well.

During a famine in 1782, Scottish highlanders complained of dropsy (an old term for edema or swelling, often associated with congestive heart failure) when they ate abundantly of potatoes.¹ Russian prisoners of World War II returned with advanced cases of dropsy, which was blamed on heavy potato consumption.² An old saying in New Hampshire in 1719 was that the white potato shortened mens lives.

Eggplant was also first grown as an ornamental, a decorative plant. It was not eaten until relatively recent years in North America. According to Dr. Norman Childers, author of The Arthritis Diet, peoples of the Mediterranean area previously believed that the eggplant would cause insanity if it was eaten daily for a month, in fact, it had the nickname of “mad apple.”³ How many foods that you eat have a reputation like that?

It’s extremely easy to overdose on nightshades in Western culture, especially if you are a foodie. Let’s say you have salsa on your eggs at breakfast, potato salad at lunch, and eggplant with peppers along with other spicy dishes at dinner. This is a large amount of nightshades, eaten three times per day, in multiple combination's. It’s very hard to avoid the nightshades, believe me, it’s a lot of work! This can be easily demonstrated by reading the menu at any restaurant— nightshades have become ubiquitous. Nightshade sensitivity, in terms of the vigilance needed to keep them out of the diet, is almost as bad as gluten sensitivity!

For those of you who think you have tried “everything” for your pain, tried this and tried that but haven’t tried avoiding nightshades— in my opinion, it’s something you do need to try. I can tell you as a IC patient, that I have tried many different remedies for my bladder and back pain. Nightshade avoidance got rid of the chronic pain I felt all over which was diagnosed as fibromyalgia and the changes in my diet, alternative therapies, and stress reduction exercises has eliminated my IC and of course I know if I go back to my old diet and lifestyle the pain and IC will rear it's ugly head again.

If you’re one of those people whose pain treatments (be it chiropractic, acupuncture, laser, energy medicine, whatever!) provides only a day or two of relief, you’re quite possibly nightshade sensitive.

A physical therapist once told me that if a patient isn’t responding to treatment, one of the first things to consider is nightshade sensitivity— there is simply nothing else that anyone can do to help somebody in pain when nightshade sensitivity is the cause—because once they eat some nightshades again, their pain will return as it was before. Sad but true, as I have experienced this many times.

This isn't to say that alternative therapies are a waste of time, this is to say try giving up nightshades and you may find that they start giving more than an hour of relief.  These therapies are a wonderful addition to your treatment plan.

 

NICOTINE (Find a support group to help you quit smoking)

All nightshades contain nicotine, which is why they can be addictive. Is nicotine a problem when we eat it? A large body of research shows that nicotine consumption inhibits proper healing.  I use to be a smoker so, I know how addictive it is and how hard it is to quit. I attended a support group, started swearing/cursing even more and was a miserable witch for the first years and gained 25 pounds which, you will be relived to know that I took off the 25 pds a year later. You have to go through it to get to the other side. 

 

TREATMENT

How do you find out whether nightshades are causing your medical problems? For many, no relief comes until the diet is totally clear of all these nightshades for at least six weeks. Many people notice an improvement in their pain; sometimes it goes away completely.

But the real question is, why are some people more sensitive than others? Nutrient deficiencies certainly come into play. For example, if you don’t have enough magnesium, you will be more prone to calcinosis. Deficiency in vitamin D may exacerbate the problem. The speed at which one’s liver and kidneys detoxify these compounds plays a huge role, and this is dependent both on genetics and nutrition.

1. Famine, Mortality, and Epidemic Disease in the Process of Modernization, by John D. Post © 1976 Economic History Society, http://www.jstor.org/ pss/2594505.
2. Childers NF. Arthritis-Childer’s Diet to Stop It. Nightshades, Aging, and Ill Health, 4th ed. Florida: Horticultural Publications, 1993; 19-21.
3. Ibid.
4. Galatz LM and others. Delayed repair of tendon to bone injuries leads to decreased biomechanical properties and bone loss. J Orthop Res. 2005 Nov;23(6):1441-7. PubMed ID: 16055296.